respimmun.at

Welcome

Description

Faculty

• Heinemann
• Höfler
• Kargl
• Kwapiszewska
• Leithner
• Marsche
• Marsh
• Moissl-Eichinger
• Olschewski A
• Olschewski H
• Strobl
Sturm ⏩
• Tomazic

Young Faculty

Students

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• Webmaster

The RESPImmun Faculty

Eva STURM, PhD

The role of JAK / STAT signaling in allergic asthma

Otto Loewi Research Centre, Division of Pharmacology, Medical University of Graz, Universitätsplatz 4, A-8010 Graz;
phone: +43-316-385 74103, fax: +43-316-385 79613,  e-mail
websites: [RESPImmun]
• Profile     • Curriculum vitae     • PhD students     • Grants     • Publications ⏬    

List of publications:

10 most significant publications:

  1. Kasatkina LA, Heinemann A, Hudz YA, Thomas D, Sturm EM: Stearoylethanolamide interferes with retrograde endocannabinoid signalling and supports the blood-brain barrier integrity under acute systemic inflammation. Biochem Pharmacol, 2020; 174:​113783.
  2. Roula D, Theiler A, Luschnig P, Sturm GJ, Tomazic PV, Marsche G, Heinemann A, Sturm EM: Apolipoprotein A-IV acts as an endogenous anti-inflammatory protein and is reduced in treatment-na├»ve allergic patients and allergen-challenged mice. Allergy, 2020; 75(2):​392–402.
  3. Theiler A, Bärnthaler T, Platzer W, Richtig G, Peinhaupt M, Rittchen S, Kargl J, Ulven T, Marsh LM, Marsche G, Schuligoi R, Sturm EM, Heinemann A: Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival. J Allergy Clin Immunol, 2019; 144(3):​764–776.
  4. Frei RB, Luschnig P, Parzmair GP, Peinhaupt M, Schranz S, Fauland A, Wheelock CE, Heinemann A, Sturm EM: Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen-induced pulmonary inflammation in mice. Allergy, 2016; 71(7):​944–956.
  5. Sturm EM, Parzmair GP, Radnai B, Frei RB, Sturm GJ, Hammer A, Schuligoi R, Lippe IT, Heinemann A: Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils. Eur J Immunol, 2015; 45(5):​1548–1559.
  6. Sturm EM, Radnai B, Jandl K, Stancic A, Parzmair GP, Högenauer C, Kump P, Wenzl H, Petritsch W, Pieber TR, Schuligoi R, Marsche G, Ferreirós N, Heinemann A, Schicho R: Opposing roles of prostaglandin D2 receptors in ulcerative colitis. J Immunol, 2014; 193(2):​827–839.
  7. Sturm EM, Dyer KD, Percopo CM, Heinemann A, Rosenberg HF: Chemotaxis of bone marrow derived eosinophils in vivo: a novel method to explore receptor-dependent trafficking in the mouse. Eur J Immunol, 2013; 43(8):​2217–2228.
  8. Sturm EM, Schuligoi R, Konya V, Sturm GJ, Heinemann A: Inhibitory effect of prostaglandin I2 on bone marrow kinetics of eosinophils in the guinea pig. J Leukoc Biol, 2011; 90(2):​285–291.
  9. Sturm EM, Schratl P, Schuligoi R, Konya V, Sturm GJ, Lippe IT, Peskar BA, Heinemann A: Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors. J Immunol, 2008; 181(10):​7273–7283.
  10. Böhm E, Sturm GJ, Weiglhofer I, Sandig H, Shichijo M, McNamee A, Pease JE, Kollroser M, Peskar BA, Heinemann A: 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. J Biol Chem, 2004; 279(9):​7663–7670.