The RESPImmun Faculty

	Gerald HÖFLER, MD LipONCO: Interaction of adipose triglyceride lipase (ATGL) with lung cancer-inducing gene mutations
Diagnostic and Research Center for Molecular Medicine, Diagnostic and Research Institute for Pathology; Medical University of Graz, Neue Stiftingtalstraße 5, A-8010 Graz; phone: +43-316-385 71737, fax: +43-316-385 79001, ✉ e-mail
websites: [RESPImmun] [DK-MCD] [MUG1] [MUG2]
• Profile     • Curriculum vitae     • PhD students     • Grants     • Publications ⏬

List of publications:

• See ⏩ Fodok Med Uni Graz

10 most significant publications:

1. Matias-Guiu X, Stanta G, Carneiro F, Ryska A, Hoefler G, Moch H; European Society of Pathology (ESP): The leading role of pathology in assessing the somatic molecular alterations of cancer: Position Paper of the European Society of Pathology. Virchows Arch, 2020; 476(4):​491–497.
2. Al-Zoughbi W, Schauer S, Pichler M, Hoefler G: Early Loss of Forkhead Transcription Factor, O Subgroup, Member 1 Protein in the Development of Pancreatic Ductal Adenocarcinoma. Pathobiology, 2018; 85(5–6):​342–347.
3. El-Heliebi A, Kashofer K, Fuchs J, Jahn SW, Viertler C, Matak A, Sedlmayr P, Hoefler G: Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer. Histochem Cell Biol, 2017; 148(2):​105–115.
4. Al-Zoughbi W, Pichler M, Gorkiewicz G, Guertl-Lackner B, Haybaeck J, Jahn SW, Lackner C, Liegl-Atzwanger B, Popper H, Schauer S, Nusshold E, Kindt AS, Trajanoski Z, Speicher MR, Haemmerle G, Zimmermann R, Zechner R, Vesely PW, Hoefler G: Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia. Oncotarget, 2016; 7(23):​33832–33840.
5. Huang J, Li L, Lian J, Schauer S, Vesely PW, Kratky D, Hoefler G, Lehner R: Tumor-Induced Hyperlipidemia Contributes to Tumor Growth. Cell Rep, 2016; 15(2):​336–348.
6. Das SK, Stadelmeyer E, Schauer S, Schwarz A, Strohmaier H, Claudel T, Zechner R, Hoefler G, Vesely PW: Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58. Int J Mol Sci, 2015; 16(4):​8555–8568.
7. Pichler M, Ress AL, Winter E, Stiegelbauer V, Karbiener M, Schwarzenbacher D, Scheideler M, Ivan C, Jahn SW, Kiesslich T, Gerger A, Bauernhofer T, Calin GA, Hoefler G: MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients. Br J Cancer, 2014; 110(6):​1614–1621.
8. Huang J, Das SK, Jha P, Al Zoughbi W, Schauer S, Claudel T, Sexl V, Vesely P, Birner-Gruenberger R, Kratky D, Trauner M, Hoefler G: The PPARα agonist fenofibrate suppresses B-cell lymphoma in mice by modulating lipid metabolism.. Biochim Biophys Acta, 2013; 1831(10):​1555–1565.
9. Tamilarasan KP, Temmel H, Das SK, Al Zoughbi W, Schauer S, Vesely PW, Hoefler G: Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity. Cell Death Diss, 2012; 3:e354.
10. Das SK, Eder S, Schauer S, Diwoky C, Temmel H, Guertl B, Gorkiewicz G, Tamilarasan KP, Kumari P, Trauner M, Zimmermann R, Vesely P, Haemmerle G, Zechner R, Hoefler G: Adipose triglyceride lipase contributes to cancer-associated cachexia. Science, 2011; 333(6039):​233–238.

31.07.2020 RESPImmun · Doctoral Programme “Immune Modulation in Respiratory Diseases”